Strategies for Reducing Risk of Elevated IRP

"While alkaline water products have a higher pH than regular water, they have a negligible alkali content–which suggests that they can't raise urine pH enough to affect the development of kidney and other urinary stones," says Roshan M. Patel, MD.

“The prevalence of kidney stones has increased over 80% over the last 30 years, and the epidemiology has changed such that it's beginning at a younger age now,” says Gregory Tasian, MD, MSc, MSCE.

"If the diversity and robust functional potential of the healthy human microbiome is repeatedly assaulted by the average Westernized lifestyle via antibiotic exposure, diet, and other environmental factors, kidney stone prevalence will continue to increase," the authors write.

“You have tradeoffs with every device that you use,” says Amy E. Krambeck, MD.

Data showed that plasma oxalate levels were maintained through 24 months of treatment with lumasiran.

Cleveland Clinic is the first to investigate photonic nanoparticles as a potential kidney stone treatment.